Skinny
Science® Coffee represents revolutionary advances in food-science,
and was named “Breakthrough Product of the Year” by Success
magazine.
PATENTED INGREDIENTS
Skinny Science® Coffee contains a unique
Patented, fat-burning blend designed to provide energy
enhancement in humans:
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|
Patented
Buffered Caffeine |
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|
Certified
Balanced-Energy Low Glycemic Fruit Base |
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|
Niacin-Bound
Chromium |
PRODUCTION OF HIGHER ENERGY LEVELS: THE MECHANISM
Skinny
Science® Coffee delivers high energy levels and
alertness in humans, not by speeding you up,
but by keeping you from slowing down.
Each
time brain cells fire, they product a squirt of
a chemical that serves as an off-switch that keeps neural
activity in check.
Skinny
Science® Coffee biochemically blocks the chemical,
and jams the switch, so it can’t be turned down. This
energy-effect can last from 2-4 hours.
Additionally,
the time-released fruit glycoside system unique to the
formula remains in the intestinal tract for a long period,
providing increased energy over a 2-to-4 hour duration.
PHYSIOLOGICAL
EFFECTS
Skinny
Science® Coffee is effective at increasing energy,
enacting thermogenesis via DIT, and adipose-tissue-fat-burning
(ATFB), via the following mechanisms:
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Stimulates under-functioning adrenal glands by increasing
the output of epinephrine and norepinephrine from
the adrenal glands. |
| • |
Stimulates
the release of catecholamines from the adrenal medulla
and releases catecholamines due to a central action
by and affecting C-AMP. |
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Donates
methyl groups in anabolic processes (Rivici Index).
|
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Increases
energy expenditure dose dependently. Stepwise regression
analysis with the thermogenic response as the dependent
variable yields the following equation: (proprietary)
as provided to our FDA-Regulatory attorneys for
Skinny Science® Coffee Thermogenics; validation
of efficacy. |
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Turns
on Brown-Fat-Thermogenesis in humans. |
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Removes adenos and phosphodiesterase blocks to thermogenesis
in humans. |
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Triggers
noradrenalin to active thermogenesis in isolated
brown adipocytes by stimulating lipolysis. |
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Inclusion
of Low Glycemic, thermogenic carbohydrates and PP
glycosides that down-regulate Lipoprotein Lipase
(LPL). |
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Inclusion
of Buffered Caffeine (full U.S. Patent) that does
not exhibit the adipose-tissue fat-storing properties
of regular caffeine. |
SKINNY
SCIENCE® COFFEE
BODY OF RESEARCH
Human In Vivo Clinical Research & Trials
|
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Anti-Carbohydrate properties, clinical studies,
and metabolic effects in humans. |
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Low
Glycemic Responses to specific Anti-Carbohydrate
Fruit Sweeteners; Human In Vivo Clinical Trials. |
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Blood
glucose effect of sugars, sweeteners and carbohydrates,
circulating adiponectin (ACRP30), metabolic syndrome
and sweeteners, genetic mutations in the leptin
gene, adipocyte glucose metabolism, decreased glucose-induced
thermogenesis (DGIT), circulating C peptide concentrations
and insulin resistance, substrate utilization of
carbohydrates and sweeteners. |
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The
Insulin-Leptin-Ghrelin relationship in energy metabolism,
improvement of glucose tolerance in type 2 diabetics
in response to acute catalytic low-dose fruit glycosides,
muscle glycogen and carbohydrates, Liporotein Lipase
(LPL) and sugars. |
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Fruit
Glycosides that do not trigger adipose tissue fat-storage,
diabetes, or insulin resistance in humans, pathogenesis
of obesity and Diet-Induced-Thermogenic (DIT) agents
in humans. |
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Thermogenic
and fat-storing response of carbohydrates, sugars
and sweeteners, stimulation of fat-storing enzymes
in humans, White and Brown Adipose Tissue (BAT)
and thermogenesis, internal vs DIT thermogenesis,
thermogenic capacity of cells and tissues. |
| • |
UCP
in mitochondria, Resistin, lipolytic actions in
humans, appestat centers of the brain, identification
and reduction of fat cell mass in humans, caloric
conversion info fat cells, human genetic code related
to deposition of adipose tissue body fat, N.E.A.T.,
fat thermostat in humans, hypothalamus-related fat-storage,
cellular level thermogenesis, caffeine and DIT. |
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Methods
for buffering caffeine to eliminate fat-storage
in fat cells, caffeine thermogenesis, LPL gatekeepers
for fat-storage in the fat cell, chromium and thermogenesis,
chocolate and Serotonin-response in human female
population. |
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Agents
that activate Serotonin, high-protein diets and
reduced thermogenesis, aging and adipose tissue
fat accumulation, adipocyte lineage, regulation
of beta-3-adrenoceptor expression in white vs brown
fat cells. |
PATHOBIOCHEMICAL & CLINICAL
ASPECTS of FAT STORAGE
Adipose tissue
(body fat) is a highly active endocrine organ secreting
a range of hormones. Energy metabolism and its regulation
determine the rate of fat-burning in an individual.
Resisten, Leptin,
Ghrelin, Adiponectin, and Lipoprotein Lipase (LPL) play
major roles in the function and storage of adipose tissue
fat in humans. Leptin (a satiety hormone), adiponectin,
and resistin are produced by adipose tissue fat cells.
LPL directs food into the fat cells, and is triggered
by ingesting high glycemic, fattening foods and/or drinks.
As fat cells
increase in size and/or number, Resistin increases, causing
increased risk of insulin resistance, obesity, and type
2 diabetes (8). Circulating adiponectin (ACRP30) levels
decrease as age progresses, which further increases risk
of insulin resistance and type 2 diabetes.
As
age increases in humans, adiponectin levels lower, triggering
increased abdominal fat deposition, disrupted carbohydrate
metabolism, and hyperlipidemia. As a result of these combined
factors, decreased thermogenesis is evidenced as humans
age and as they gain weight.
PATENTED
THERMOGENIC FAT-BURNING
The
form of thermogenesis in humans activated by Skinny
Science® Coffee called Diet-Induced-Thermogenesis
(DIT) and is well known in the scientific literature.
Skinny
Science® Coffee produces a DIT thermogenic effect,
de novo lipogenesis, as well as carbohydrate oxidation
(burning) in a Proprietary Low Glycemic matrix.
SKINNY SCIENCE® COFFEE ANTI-GLUCOSE
MATRIX
Skinny Science® Coffee contains a specially
formulated ANTI-GLUCOSE MATRIX that addresses key areas
in fat-burning metabolism:
In order to combat Stress-Related-Eating (SRE) and False-Food-Cravings,
the human body requires the opposite of Glucose-elevation,
which is a Low Glycemic Matrix.
A Low Glycemic Matrix does not stimulate glucose, and
conversely helps block False-Food-Cravings. The
unique Matrix found in Skinny Science® Coffee
provides a mechanism for blocking fat-storage
and glucose-fat-storage.
The human body, and specifically the brain, requires at
least 130 grams of carbohydrates per day for cognitive
function and energy. Low energy levels and impaired cognitive
function are typical when following a low carb diet.
High glycemic carbohydrates cause glucose and blood sugar
swings, fat-storage, and weight gain.
High protein, and low carb diets and foods, exacerbate
(worsen) the biochemical stress machine by depriving the
body of stress-calming carbohydrates.
Thermogenic drinks and compounds that do not contain a
Low Glycemic Matrix cause fat-storage.
STRESS LEADS TO WEIGHT GAIN
Stress, as every woman can attest, causes weight gain.
The link between stress and weight gain has been scientifically
proven. At Georgetown University Medical Center,
researchers showed that stress conditions cause weight
gain, even when caloric intake does not vary.
Stress,
experienced as a part of everyday life, triggers the body’s
conversion of food energy into glucose as a fight-or-flight
hard-wired mechanism. Neuropeptide Y (NPY) is elevated
during stress.
NPY
attaches to a receptor, a molecular doorway, in fat cells
that is called Neuropeptide Y2 receptor, or Y2R. It activates
fat cells and some of the cells in blood vessels found
in fat tissue.
This cascade of fat-storage mechanisms leads to weight
gain as well as depletion of specific B vitamins (particularly
B-6), as they are utilized in the Glucose-Producing-Reaction
(GPR). As glucose and NPY levels rise, weight gain increases
in adipose tissue fat cells.
The human body is hard-wired to gain belly-fat under stress,
even mild chronic stress.
STRESS EATING
Stress-Related-Eating (SRE) is caused by biochemical reactions
in the body that trigger False-Food-Cravings.
A perfect example of this reaction is PMS, which is generally
accompanied by cravings for chocolate, sweets, crunchy
foods, and sweet-salty foods (such as chocolate-covered
potato chips).
Stress-Related-Eating (SRE) leads to weight gain because
the foods carved during SRE elevate glucose production
and adipose tissue fat storage. Glucose-elevating foods
are High Glycemic. They help sooth stress, but also stimulate
fat-storage.
SKINNY SCIENCE® COFFEE
DESIGNED BY LEADING GLYCEMIC INDEX RESEARCHERS
Why is it important
to have glycemic researchers design an energy drink?
Because energy
drinks cause FAT-STORAGE in humans. What is the point
of energizing the body and stimulating fat-storage at
the same time?
The
only way to engineer an energy drink that does not stimulate
fat-storage is to incorporate the Glycemic Index (Glycemic.com)
and the Cephalic Response (CephalicResearch.com) into
the equation and to use Buffered Caffeine instead of regular
caffeine.
CERTIFICATIONS
Skinny
Science® Coffee is certified by the Glycemic
Research Institute®, Skinny Science™, Natural Beverages,
and Human Sports Performance:
www.SkinnyScience.com
www.GlycemicResearchInstitute.com
www.HumanSportsPerformance.com
www.NaturalBev.com
COPY-CAT PRODUCTS
Skinny
Science® Coffee cannot be copied due
to the non-reverse-engineerable formula, proprietary manufacturing
process, and strong Patent status.
The
information and science found herein is Copyright, Trademark,
and Patent protected by the United States Federal government.
CONTRAINDICATIONS
Taking
Skinny Science® Coffee too close to bedtime
may result in difficulty falling asleep, due to the energy-enhancing
effects.
